The world reached a grim milestone on Sunday as the number of coronavirus deaths passed 500,000, according to data from Johns Hopkins University.

As of Sunday evening, over 10 million coronavirus cases and more than 501,000 deaths had been reported around the globe, according to the Johns Hopkins COVID-19 dashboard. Several countries, including Germany, Brazil, and India, have recently seen new infections spike.

The US has recorded the most coronavirus deaths of any country, with more than 125,000.

According to CNN, 36 US states are seeing increases in new coronavirus cases. The US on multiple days last week reported record single-day increase of infections, with at least 40,173 new cases on Friday.

Health and Human Services Secretary Alex Azar on Sunday said the “window is closing” for the US to control its coronavirus outbreak.

Speaking with NBC’s “Meet the Press,” Azar urged Americans to “act responsibly” by practicing social distancing and wearing face coverings as states reopened.

Last week, the Centers for Disease Control and Prevention’s director, Robert Redfield, acknowledged that the number of Americans who had been infected with the novel coronavirus was probably far higher than the official count.

“Our best estimate right now is that for every case that’s reported, there actually are 10 other infections,” he told reporters on Thursday.

Redfield’s acknowledgment echoes what researchers have been saying for months about the likelihood of a higher coronavirus count, particularly in countries with severe outbreaks.

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