Saoirse Kennedy Hill, the granddaughter of Robert F Kennedy, has died, a family statement has confirmed.
The 22-year-old daughter of Robert and Ethel Kennedy’s fifth child, Courtney, died on Thursday.
Emergency services were called to the Kennedy residence in Hyannis Port, Massachusetts. Ms Kennedy Hill was pronounced dead at Cape Cod Hospital.
The Kennedy family has seen a number of tragedies including the assassination of Saoirse’s grandfather in 1968.
“Our hearts are shattered by the loss of our beloved Saoirse. Her life was filled with hope, promise and love,” the family said in a statement.
A statement from her grandmother added: “The world is a little less beautiful today.”
No further details about her death have been released, although US media report she died of an apparent overdose.
The 22-year-old was a communications major at Boston College, according to the New York Times, and had suffered from depression.
“My depression took root in the beginning of my middle school years and will be with me for the rest of my life,” she wrote in a student newspaper in 2016.
Police said they were called to a report of “an unattended death” and have launched an investigation.
The compound was the summer White House for President John F Kennedy, Ms Kennedy Hill’s great uncle, in the 1960s. He was assassinated in Dallas in 1963.
July marked 20 years since the death of President Kennedy’s son, John F Kennedy Jr. He was piloting a light aircraft to a wedding at Hyannis Port, but crashed into the sea en route.